Theoretical Biology & Bioinformatics

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Rob J. de Boer

Rob J. de Boer

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Estimating relative fitness from competition experiments

You have estimated the percentages (or fractions) of mutant and wild virus at the start and at the end of a competition experiment. You also know the initial and the final viral load in your experiment. You may have a third group of unrelated mutants. This can be represented in the boxes summed percentage. The sum of the mutant and wild type percentages will be less than a 100% when the data involve more than two variants.

Length of experiment in days: Death rate of infected cells (delta):
Initial virus value: Final virus value:
Initial percentage mutant: Final percentage mutant:
Initial summed percentage: Final summed percentage:
Dilution factor (1 means no dilution):