>Bat_CV_HKU8 coronavirus spike 
MKSLLVLSLLALLATLSVNAQVTGEGGVAEGNYWVNASCAGWSYFYALKLGLPPNASAIVTGYLPKPKGW
ICPRFNGAGIYTRNNANAVFVMYRTKALAFEIGVSSSAGGEQYSAYMAQQNGKYLVLRICKWQNGTLAAP
TLQSTSGKDCIVNVKVDNHMFYHAAHDIVGMSWSGDAVRLYTQTDTKTYYIPNSWDRVSIRCPDKFSCSS
QIVTKAITVNVTTFANGTIDKYAICDNCNGYPAHIFPVSEGGLIPADFNFSNWFLLTNSSTIVDGRIVSE
QPVLLMCLWAVPGLMSTNSFVYFNGTAPNKQCNGYATDSAFEALRFSLNFTDERVFAGSGSVVLLVSGLQ
YKFSCTNNSEAVIDSGIPFGNVVEPFYCFVSINGTSIFVGMLPAVLREIVITRYGSIYLNGFSIFQGPPI
QGVLFNVTNRGATDLWTVALSNFTEVLAEVQSTAIKALLYCDDPLSQLKCQQLQFSLPDGFYATASLFQH
ELPRTFVTLPRHFTHSWINLRIKWKNGVCYNCPPASSWIDFVTFNSNGTENVLPERTLCVNTTQFTTNLT
LIEEAFSYSTPVVVRADDCPFDFQSLNNYLTFGSICFSLNGTIGKGCTLGIYKRASSQYIPIWNVWVAYT
SGDNILGVREPNVGVRDQSVVHQNVCTSYTIFGHSGRGIIRPANISYIAGVYYTAASGQLLGFKNTTTGE
VFSVTPCNPSQQAVVVKDRLVGVMSSTSTVSIPFNNTIPTPSFYYHSNATSSCDDPSVVYSSIGICDDGG
ITFVNSTRVRGEPDPAISMGNISVPSNFTVSIQVEYLQMSIRPVSIDCAMYVCNGNPHCTRLLQQYISAC
RTIEEALQLSARLESFEVNSMLTVSETALDLVNISTFGGDYNLTALLPQGGGKRSVIEDILFDKVVTSGL
GTVDEDYKRCTNGIGIADVPCAQYYNGIMVLPGVVDEEKMSIYTASLLGGMTMGGFTPVAALPFALSVQS
RLNYVALQTDVLQKNQQILANAFNSAIGNITVAFDQVTTAVQQTSDAIKTVASALNKVQSVVNSQGQALH
QLTKQLASNFQAISASIEDIYNRLDGLAADANVDRLITGRLAALNAFVTQTLTKYTEVRASRLLAQEKIN
ECVKSQSTRYGFCGNGTHLFSIPNAAPEGIMLFHTVLVPTEYVSVTAWSGYCHNGVGYAVKDVGNSLFQF
NNTFYITPRNMYQPRTPTSADFIRISGCNVVYVNITDEQLPQVQPEFIDVNKTLEELMSRLPNNTGPNLP
LDIFNQTYLNISAEIDALENKSLELQATADKLQLTIEQLNATLVDLEWLNRFEQYVKWPWWVWLTMIIAL
VLLTGLMLWCCLATGCCGCCSCMASTLDFRGSRLQQYEVEKVHIQ
>Bat_CV_Rp3 spike protein 
MKILILAFLASLAKAQEGCGIISRKPQPKMAQVSSSRRGVYYNDDIFRSNVLHLTQDYFLPFDSNLTQYF
SLNVDSDRFTYFDNPILDFGDGVYFAATEKSNVIRGWIFGSTFDNTTQSAVIVNNSTHIIIRVCNFNLCK
EPMYTVSRGAQQSSWVYQSAFNCTYDRVEKSFQLDTAPKTGNFKDLREYVFKNRDGFLSVYQTYTAVNLP
RGLPIGFSVLRPILKLPFGINITSYRVVMAMFSQTTSNFLPESAAYYVGNLKYTTFMLSFNENGTITNAI
DCAQNPLAELKCTIKNFNVSKGIYQTSNFRVSPTQEVIRFPNITNRCPFDKVFNATRFPNVYAWERTKIS
DCVADYTVLYNSTSFSTFKCYGVSPSKLIDLCFTSVYADTFLIRSSEVRQVAPGETGVIADYNYKLPDDF
TGCVIAWNTAKQDQGQYYYRSHRKTKLKPFERDLSSDENGVRTLSTYDFYPSVPVAYQATRVVVLSFELL
NAPATVCGPKLSTQLVKNQCVNFNFNGLKGTGVLTESSKRFQSFQQFGRDTSDFTDSVRDPQTLEILDIS
PCSFGGVSVITPGTNASSEVAVLYQDVNCTDVPAAIHADQLTPAWRVYSTGTNVFQTQAGCLIGAEHVNA
SYECDIPIGAGICASYHTASTLRSVGQKSIVAYTMSLGAENSIAYANNSIAIPTNFSISVTTEVMPVSMA
KTSVDCTMYICGDSLECSNLLLQYGSFCTQLNRALSGIAIEQDKNTQEVFAQVKQMYKTPAIKDFGGFNF
SQILPDPSKPTKRSFIEDLLFNKVTLADAGFMKQYGECLGDISARDLICAQKFNGLTVLPPLLTDEMIAA
YTAALVSGTATAGWTFGAGSALQIPFAMQMAYRFNGIGVTQNVLYENQKQIANQFNKAISQIQESLTTTS
TALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQL
IRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQAAPHGVVFLHVTYVPSQERNFTTAPAIC
HEGKAYFPREGVFVSNGTSWFITQRNFYSPQIITTDNTFVAGSCDVVIGIINNTVYDPLQPELDSFKEEL
DKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKWPWYVWLGFIA
GLIAIVMVTILLCCMTSCCSCLKGACSCGSCCKFDEDDSEPVLKGVKLHYT
>Bat_CV_HKU3-1 spike protein
MKILIFAFLANLAKAQEGCGIISRKPQPKMAQVSSSRRGVYYNDDIFRSDVLHLTQDYFLPFDSNLTQYF
SLNVDSDRYTYFDNPILDFGDGVYFAATEKSNVIRGWIFGSSFDNTTQSAVIVNNSTHIIIRVCNFNLCK
EPMYTVSRGTQQNAWVYQSAFNCTYDRVEKSFQLDTTPKTGNFKDLREYVFKNRDGFLSVYQTYTAVNLP
RGLPTGFSVLKPILKLPFGINITSYRVVMAMFSQTTSNFLPESAAYYVGNLKYSTFMLRFNENGTITDAV
DCSQNPLAELKCTIKNFNVDKGIYQTSNFRVSPTQEVIRFPNITNRCPFDKVFNATRFPNVYAWERTKIS
DCVADYTVLYNSTSFSTFKCYGVSPSKLIDLCFTSVYADTFLIRSSEVRQVAPGETGVIADYNYKLPDDF
TGCVIAWNTAKHDTGNYYYRSHRKTKLKPFERDLSSDDGNGVYTLSTYDFNPNVPVAYQATRVVVLSFEL
LNAPATVCGPKLSTELVKNQCVNFNFNGLKGTGVLTSSSKRFQSFQQFGRDTSDFTDSVRDPQTLEILDI
SPCSFGGVSVITPGTNASSEVAVLYQDVNCTDVPTAIRADQLTPAWRVYSTGVNVFQTQAGCLIGAEHVN
ASYECDIPIGAGICASYHTASVLRSTGQKSIVAYTMSLGAENSIAYANNSIAIPTNFSISVTTEVMPVSM
AKTAVDCTMYICGDSLECSNLLLQYGSFCTQLNRALTGIAIEQDKNTQEVFAQVKQMYKTPAIKDFGGFN
FSQILPDPSKPTKRSFIEDLLFNKVTLADAGFMKQYGDCLGDVSARDLICAQKFNGLTVLPPLLTDEMVA
AYTAALVSGTATAGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQESLSST
ASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQ
LIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPSQEKNFTTAPAI
CHEGKAYFPREGVFVSNGTSWFITQRNFYSPQLITTDNTFVSGNCDVVIGIINNTVYDPLQPELDSFKEE
LDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKWPWYVWLGFI
AGLIAIVMVTILLCCMTSCCSCLKGACSCGSCCKFDEDDSEPVLKGVKLHYT
>Equine spike protein [Equine coronavirus NC99]
MVLLLLFFLPGAFAVVGDVKCTTTGVNNFNSGAPVISTETVDVTNGLGTYYVLDRVYLNTTLLLNGYYPT
SGANYRNLALKASGLLSTLWYKPPFLSEFNDGVFAKVKNTKVTKNGIVYSEFPTMAIGTTFVNTSYTVVV
QPRTTVVNSKLQGLLEITICQYSMCEYPNTVCNSGIGSPRKELWHYEKAVASCLYRRNFTYDVNSDWLYF
HFYQQGGTFYAYYTDSGFITTFLFNIYLGTSLSHYYVMPLSCSGKLDLQYWVTPLTNRQFLLVFNQDGII
YNAVDCASDYMSEIKCNTQNVKPSTGVYDLTGYTVQPIADVYRRIPNLPDCNMEDWLSAPTVASPLNWER
RTFSNCNFNMSSLMSFIQADSFSCSNIDAAKLYGMCFGSVTIDKFAIPNSRKVDLQLGNLGYLQSFNYRI
DTTATSCQLYYSLGADNVTVTRSNPSAWNRRYGFNDTMFKPQPAGFFTNHDVVYSKQCFKVPNTYCPCKN
NGATCVGNGISAGVSGTTTGSGTCPVGTSYRTCFNPIQCACTCDPEPINAILTSGPRACPQVKSLVGLGE
HCSGLGIHEDFCGGSPCSCPANAFMAWSADSCLQDGRCNIFSNLILNGVNSGATCSTDLQRSNTEIVVGV
CVKYDLYGITGQGIFIEVNATYYNSWQNLLYDSNGNLYGFRDYLTNRTFMIRSCYSGRVSAAYHSDASEP
ALLYRNLKCNYVFNNTIAREGNPINYFDSYLGCIVNADNSTSSVVDTCVLTMGSGYCVDYSTARRQRRSP
STGYRLTNFEPFNVRLVNDSVEPVGGLYEIQIPSEFTIGNFEEFIQTNSPKVTIDCAAFVRGDYAACREQ
LVEYGSFCDNINAILTEVNDLLDTTQFQVANSLMNGVTLSSRLKTGINFNVDDINFSSVLGCVGSDCNTV
SSRSAIEDLLFNKVRLSDVGFVEAYNNCTGGAEIRDLLCVQTFNGIKVLPPVLSENQISGYTLAATSASL
FPPWTAAAGIPFYLNVQYRINGLGVTMDVLSQNQKMIANAFNNALGAIQNGFDATNSALVKIQAVVNANA
EALNNLLQQLSNRFGAISSSLQEILSRLDALEAQAQIDRLINGRLTALNAYVSQQLSDTTLVKFSASQAI
EKVNECVKSQSLRVNFCGNGNHIISLVQNAPYGLYFIHFNYVPTKYVTAKVSPGLCIAGDKGIAPKSGYF
VNVNNIWMFTGSGYYYPEPITENNVVVMSTCAVNYTKAPDVMLNISIPNLPDFKEELDQWFKNQTSVAPD
LSLDYINVTFLNLQDEMNRLQESIKVLNQSYINLKDIGTYEYYVKWPWYVWLLIGLAGVAMLVLLFFICC
CTGCGTSCFKKCGGCCDDYTGHQELVIKTSHDD
>Porcine spike protein [Porcine epidemic diarrhea virus]
MRSLIYFWLLLPVLPTLSLPQDVTRCQSTTNFRRFFSKFNVQAPAVVVLGGYLPSMNSSSWYCGTGIETA
SGVHGIFLSYIDSGQGFEIGISQEPFDPSGYQLYLHKATNGNTNAIARLRICQFPDNKTLGPTVNDVTTG
RNCLFNKAIPAYMRDGKDIVVGITWDNDRVTVFADKIYHFYLKNDWSRVATRCYNRRSCAMQYVYTPTYY
MLNVTSAGEDGIYYEPCTANCTGYAANVFATDSNGHIPEGFSFNNWFLLSNDSTLLHGKVVSNQPLLVNC
LLAIPKIYGLGQFFSFNHTMDGVCNGAAVDRAPEALRFNINDTSVILAEGSIVLHTALGTNLSFVCSNSS
DPHLAIFAIPLGATEVPYYCFLKVDTYNSTVYKFLAVLPPTVREIVITKYGDVYVNGFGYLHLGLLDAVT
INFTGHGTDDDVSGFWTIASTNFVDALIEVQGTSIQRILYCDDPVSQLKCSQVAFDLDDGFYPISSRNLL
SHEQPISFVTLPSFNDHSFVNITVSAAFGGLSSANLVASDTTINGFSSFCVDTRQFTITLFYNVTNSYGY
VSKSQDSNCPFTLQSVNDYLSFSKFCVSTSLLAGACTIDLFGYPAFGSGVKLTSLYFQFTKGELITGTPK
PLEGITDVSFMTLDVCTKYTIYGFKGEGIITLTNSSILAGVYYTSDSGQLLAFKNVTSGAVYSVTPCSFS
EQAAYVNDDIVGVISSLSNSTFNNTRELPGFFYHSNDGSNCTEPVLVYSNIGVCKSGSIGYVPPQYGQVK
IAPTVTGNISIPTNFSMSIRTEYLQLYNTPVSVDCATYVCNGNSRCKQLLTQYTAACKTIESALQLSARL
ESVEVNSMLTISEEALQLATISSFNGDGYNFTNVLGASVYDPASGRVVQKRSVIEDLLFNKVVTNGLGTV
DEDYKRCSNGRSVADLVCAQYYSGVMVLPGVVDAEKLHMYSASLIGGMALGGITAAAALPFSYAVQARLN
YLALQTDVLQRNQQLLAESFNSAIGNITSAFESVKEAISQTSKGLNTVAHALTKVQEVVNSQGSALNQLT
VQLQHNFQAISSSIDDIYSRLDILSADVQVDRLITGRLSALNAFVAQTLTKYTEVQASRKLAQQKVNECV
KSQSQRYGFCGGDGEHIFSLVQAAPQGLLFLHTVLVPGDFVNVLAIAGLCVNGEIALTLREPGLVLFTHE
LQNYTATEYFVSSRRMFEPRKPTVSDFVQIESCVVTYVNLTSDQLPDVIPDYIDVNKTLDEILASLPNRN
GPSLPLDVFNATYLNLTGEIADLEQRSESLRNTTEELRSLINNINNTLVDLEWLNRVETYIKWPWWVWLI
IFIVLIFVVSLLVFCCISTGCCGCCGCCGACFSGCCRGPRLQPYEAFEKVHVQ
>Feline S [Feline coronavirus]
MIVLVTCLLLLCSYHTVLSTTNNECIQVNVTQLAGNENLIRDFLFSNFKEEGSVVVGGYYPTEVWYNCSR
TARTTAFQYFNNIHAFYFVMEAMENSTGNARGKPLLFHVHGEPVSVIISAYRDDVQQRPLLKHGLVCITK
NRHINYEQFTSNQWNSTCTGADRKIPFSVIPTDNGTKIYGLEWNDDFVTAYISGRSYHLNINTNWFNNVT
LLYSRSSTATWEYSAAYAYQGVSNFTYYKLNNTNGLKTYELCEDYEHCTGYATNVFAPTSGGYIPDGFSF
NNWFLLTNSSTFVSGRFVTNQPLLINCLWPVPSFGVAAQEFCFEGAQFSQCNGVSLNNTVDVIRFNLNFT
ADVQSGMGATVFSLNTTGGVILEISCYSDTVSESSSYSYGEIPFGITDGPRYCYVLYNGTALKYLGTLPP
SVKEIAISKWGHFYINGYNFFSTFPIGCISFNLTTGVSGAFWTIAYTSYTEALVQVENTAIKNVTYCNSH
INNIKCSQLTANLNNGFYPVASSEVGFVNKSVVLLPSFFTYTAVNITIDLGMKLSGYGQPIASTLSNITL
PMQDNNTDVYCIRSNQFSVYVHSTCKSSLWDNIFNQDCTDVLEATAVIKTGTCPFSFDKLNNYLTFNKFC
LSLSPVGANCKFDVAARTRTNEQVVRSLYVIYEEGDNIVGVPSDNSGLHDLSVLHLDSCTDYNIYGRTGV
GIIRRTNSTLLSGLYYTSLSGDLLGFKNVSDGVIYSVTPCDVSVQAAVIDGAIVGAMTSINSELLGLTHW
TTTPNFYYYSIYNYTSERTRGTAIDSNDVDCEPVITYSNIGVCKNGALVFINVTHSDGDVQPISTGNVTI
PTNFTISVQVEYMQVYTTPVSIDCARYVCNGNPRCNKLLTQYVSACQTIEQALAMGARLENMEVDSMLFV
SENALKLASVEAFNSTENLDPIYKEWPSIGGSWLGGLKDILPSHNSKRKYGSAIEDLLFDKVVTSGLGTV
DEDYKRCTGGYDIADLVCAQYYNGIMVLPGVANADKMTMYTASLAGGITLGALGGGAVAIPFAVAVQARL
NYVALQTDVLNKNQQILANAFNQAIGNITQAFGKVNDAIHQTSQGLATVAKALAKVQDVVNTQGQALSHL
TVQLQNNFQAISSSISDIYNRLDELSADAQVDRLITGRLTALNAFVSQTLTRQAEVRASRQLAKDKVNEC
VRSQSQRFGFCGNGTHLFSLANAAPNGMIFFHTVLLPTAYETVTAWSGICASDGDRTFGLVVKDVQLTLF
RNLDDKFYLTPRTMYQPRVATSSDFVQIEGCDVLFVNATVIDLPSIIPDYIDINQTVQDILENYEPNWTV
PEFTLDIFNATYLNLTGEIDDLEFRSEKLHNTTVELAILIDNINNTLVNLEWLNRIETYVKWPWYVWLLI
GLVVVFCIPLLLFCCFSTGCCGCIGCLGSCCHSICSRRQFENYEPIEKVHVH
>Canine spike protein [Canine coronavirus]
MIVLTLCLLLFSYNSVICTSNNDCVQVNVTQLPGNENIIKDFLFHTFKEEGSVVVGGYYPTEVWYNCSRS
ATTTAYKDFSNIHAFYFDMEAMENSTGNARGKPLLVHVHGDPVSIIIYISAYRDDVQGRPLLKHGLLCIT
KNKIIDYNTFTSAQWSAICLGDDRKIPFSVIPTDNGTKIFGLEWNDDYVTAYISDRSHHLNINNNWFNNV
TILYSRSSTATWQKSAAYVYQGVSNFTYYKLNNTNGLKSYELCEDYEYCTGYATNVFAPTVGGYIPDGFS
FNNWFMLTNSSTFVSGRFVTNQPLLVNCLWPVPSFGVAAQQFCFEGAQFSQCNGVSLNNTVDVIRFNLNF
TTDVQSGMGATVFSLNTTGGVILEISCYNDTVSESSFYSYGEISFGVTDGPRYCFALYNGTALKYLGTLP
PSVKEIAISKWGHFYINGYNFFSTFPIDCISFNLTTGDSGAFWTIAYTSYTDALVQVENTAIKKVTYCNS
HINNIKCSQLTANLQNGFYPVASSEVGLVNKSVVLLPSFYSHTSVNITIDLGMKRSGYGQPIASTLSNIT
LPMQDNNTDVYCIRSNRFSVYFHSTCKSSLWDDVFNSDCTDVLYATAVIKTGTCPFSFDKLNNYLTFNKF
CLSLNPVGANCKFDVAARTRTNEQVVRSLYVIYEEGDNIVGVPSDNSGLHDLSVLHLDSCTDYNIYGITG
VGIIRQTNSTLLSGLYYTSLSGDLLGFKNVSDGVIYSVTPCDVSAHAAVIDGAIVGAMTSINSELLGLTH
WTTTPNFYYYSIYNYTNERTRGTAIDSNDVDCEPIITYSNIGVCKNGALVFINVTHSDGDVQPISTGNVT
IPTNFTISVQVEYIQVYTTPVSIDCSRYVCNGNPRCNKLLTQYVSACQTIEQALAMGARLENMEIDSMLF
VSENALKLASVEAFNSTETLDPIYKEWPNIGGSWLGGLKDILPSHNSKRKYRSAIEDLLFDKVVTSGLGT
VDEDYKRCTGGYDIADLVCAQYYNGIMVLPGVANDDKMAMYTASLAGGITLGSLGGGAVSIPFAIAVQAR
LNYVALQTDVLNKNQQILANAFNQAIGNITQAFGKVNDAIHQTSQGLATVAKVLAKVQDVVNTQGQALSH
LTVQLQNNFQAISSSISDIYNRLDELSADAQVDRLITGRLTALNAFVSQTLTRQAEVRASRQLAKDKVNE
CVRSQSQRFGFCGNGTHLFSLANAAPNGMIFFHTVLLPTAYETVTAWSGICASDGDRTFGLVVKDVQLTL
FRNLDDKFYLTPRTMYQPRVATSSDFVQIEGCDVLFVNATVIDLPSIIPDYIDINQTVQDILENFRPNWT
VPELPLDIFNATYLNLTGEINDLEFRSEKLHNTTVELAILIDNINNTLVNLEWLNRIETYVKWPWYVWLL
IGLVVIFCIPILLFCCCSTGCCGCIGCLGSCCHSICSRRQFESYEPIEKVHVH
>Human_CV human coronavirus spike glycoprotein [Human coronavirus 229E]
MFVLLVAYALLHIAGCQTTNGLNTSYSVCNGCVGYSENVFAVESGGYIPSDFAFNNWFLLTNTSSVVDGV
VRSFQPLLLNCLWSVSGLRFTTGFVYFNGTGRGDCKGFSSDVLSDVIRYNLNFEENLRRGTILFKTSYGV
VVFYCTNNTLVSGDAHIPFGTVLGNFYCFVNTTIGTETTSAFVGALPKTVREFVISRTGHFYINGYRYFT
LGNVEAVNFNVTTAETTDFFTVALASYADVLVNVSQTSIANIIYCNSVINRLRCDQLSFYVPDGFYSTSP
IQSVELPVSIVSLPVYHKHMFIVLYVDFKPQSGGGKCFNCYPAGVNITLANFNETKGPLCVDTSHFTTKY
VAVYANVGRWSASINTGNCPFSFGKVNNFVKFGSVCFSLKDIPGGCAMPIVANWAYSKYYTIGTLYVSWS
DGDGITGVPQPVEGVSSFMNVTLDKCTKYNIYDVSGVGVIRVSNDTFLNGITYTSTSGNLLGFKDVTKGT
IYSITPCNPPDQLVVYQQAVVGAMLSENFTSYGFSNVVELPKFFYASNGTYNCTDAVLTYSSFGVCADGS
IIAVQPRNVSYDSVSAIVTANLSIPSNWTISVQVEYLQITSTPIVVDCSTYVCNGNVRCVELLKQYTSAC
KTIEDALRNSARLESADVSEMLTFDKKAFTLANVSSFGDYNLSSVIPSLPTSGSRVAGRSAIEDILFSKI
VTSGLGTVDADYKNCTKGLSIADLACAQYYNGIMVLPGVADAERMAMYTGSLIGGIALGGLTSAVSIPFS
LAIQARLNYVALQTDVLQENQKILAASFNKAMTNIVDAFTGVNDAITQTSQALQTVATALNKIQDVVNQQ
GNSLNHLTSQLRQNFQAISSSIQAIYDRLDTIQADQQVDRLITGRLAALNVFVSHTLTKYTEVRASRQLA
QQKVNECVKSQSKRYGFCGNGTHIFSIVNAAPEGLVFLHTVLLPTQYKDVEAWSGLCVDGTNGYVLRQPN
LALYKEGNYYRITSRIMFEPRIPTMADFVQIENCNVTFVNISRSELQTIVPEYIDVNKTLQELSYKLPNY
TVPDLVVEQYNQTILNLTSEISTLENKSAELNYTVQKLQTLIDNINSTLVDLKWLNRVETYIKWPWWVWL
CISVVLIFVVSMLLLCCCSTGCCGFFSCFASSIRGCCESTKLPYYDVEKIHIQ
>Turkey spike glycoprotein precursor [Turkey coronavirus]
MLVQLCCLTILLSLVCNVSSITTICNNATVGSGVCISCTNIPEYADGKNGGEALDFYSPDVMRPSDGAYI
QSGYYEPLFTGCFNQTNQTDTTCKNGLYAGSPGNFTIQGGFLQNYDAIGIMFWWGIGTNADKKSNDPIFN
LTWGNFFLNFTGFPKVKSVIFIATGDIFVNGVLMGVYNLNFTQTLTIWLAQCVGTMKVVILRNSNALVHF
SAGNVVAFEPCTGDTTINKLRCAYQQFNFSTGFYDIDTFVPVTPNITHLPYPDLKDNTSQEVHEFYVALK
GDPVNYNQSCVDSKYSFFKLKCNNTYSWDFDKLYTLGSEIYVPGYNVYTNTATFICRHYTQIIQLVLPKG
LSLENIYNNIGFNRFCVTKLLETRDISSITQYTCVYVVSVEGFDSYHSGLKYSYVGVNFDFGTAMYSVKS
APKQFIYTEQCHNYNIYNIRGVGQILNVTGKDNTTLVDGGLAITSGSGLLAFRNNGSLYSVQPCQTVSTQ
AVIVNGSFVGLFVPASCRLAQQFNLGNHTEYVDGGCLISNKTTIRMRRSTSAVYTGECIGLFVAMGKSCI
YSNGTVLNRTLPQSSVQTSVQPLLGVVANVSIPKELTLAVTTEYLQTRYQKVTIDCAKYVCGDSARCRTL
LQQYGSFCQSINAILSGVNENEDNGLLQYAEAINTGYTLNFTGYNVSNLGGFDLSLVLPKNLTLLQNQGR
STIEDLLFDKVVTLGVSEVDQNYDKCIASRGGSFTNLADLTCAQFYNGVMVLPGVVDPGLMAVYTGSLIG
GMALGGITAAASIPFATQIQARVNYLALTQSVLLDNQNLIANSFNKALKGIQSALDTMSNGFAEVAKGFE
SVTVALNKVQDVVNTHSDILNKLMAQLSVNFGAVSSSLNEIYLKLDQINADAQVDRLITGRLTALSTYVA
SLQLAAYKADQSRRLALQEVEECVKSQSMRYGFCGNGSHVLTIPQSAPNGIFFIHYTYQPTVYVTIEAVP
GLCVTTPSGKYGECPRLEVASYLDRMVLSLSLPHSYXEPKLLSYSEVVNLTSCEANYYNVSESETPFQPA
LPNFDDEFNDIFTELNTSKDAIKNISSNFNYTIPILDLQDEICRLNHSINTLYNYSDVIDKINQGLNDTF
INLEQLNKITRYIKWPWYVWLAIGFACLIFILILGWVFFMTGCCGCCCGCFGIIPLMSKCGKKSSYYTTF
DNDVVYEQYRPKKSV
>Avian spike glycoprotein [Avian infectious bronchitis virus]
MLGKSLFLVTILCALCSANLFNSGNYVYYYQSAFRPPNGWHLQGGAYAVVNSTNHTSNAGSASQCTVGVI
KDVYNQSAASIAMTAPLQGMAWSKSAFCSAHCNFSEITVFVTHCYSSGPMSCPITGMIARDHIRISAMKN
GSLFYNLTVSVSKYPNFKSFQCVNNYTSVYLNGDLVFTSNKTTDVTAAGVYFKAGGPVNYSIMKEFKVLA
YFVNGTVQDVILCDNSPKGLLACQYNTGNFSDGFYPFTNSTLVREKFIVYRESSVNTTLALTNFTFTNVS
NAPPNSGGVHTFHLYQTQTAQSGYYKFNLSFLSQFVYKASDYMYGSYHPSCSFRPETINNGLWFNSLSVS
LTYGPLQGGCKQSVFSGKATCCYAYSYNGPRACKGVYLGELSTNFECGLLVYVTKSDGSRIQTRTEPLVL
TQHNYNNITLDKCVAYNIYGRVGQGFITNVTDSAANFSYLADGGLAILDTSGAIDVFVVQGSYGLNYYKV
NPCEDVNQQFVVSGGNIVGILTSRNETGSEQVENQFYVKLTNSSHRRRRSIGQNVTSCSYVSYGRFCIEP
DGSLKMIVPEELKQFVAPLLNITESVLIPNSFNLTVTDEYIQTRMDKVQINCLQYVCGSSLECRKLFQQY
GPVCDNILSVVNSVSQKEDMELLSFYSSTKPKGYDTPVLSNVSTGQFNISLLLTPPSSPSGRSFIEDLLF
TSVETVGLPTDAEYKKCTAGPLGTLKDLICAREYNGLLVLPPIITADMQTMYTASLVGAMAFGGITSAAA
IPFATQIQARINHLGITQSLLMKNQEKIAASFNKAIGHMQEGFRSTSLALQQVQDVVNKQSAILTETMNA
LNKNFGAISSVIQDIYAQLDAIQADAQVDRLITGRLSSLSVLASAKQSEYIRVSQQRELATQKINECVKS
QSNRYGFCGSGRHVLSIPQNAPNGIVFIHFTYTPESFVNVTAIVGFCVNPANASQYAIVPANGRGIFIQV
NGSYYVTARDMYMPRDITAGDIVTLTSCQANYVNVNKTVITTFVEDDDFNFDDELSKWWNDTKHELPDFE
DFNYTVPILNISGEIDHIQGVIQGLNDSLINLEELSIIKTYIKWPWYVWLAIGFAIIIFILILGWVFFMT
GCCGCCCGCFGIIPLMSKCGKKSSYYTTFDNDVVTEQYRPKKSV
>Bovine spike glycoprotein precursor [Bovine coronavirus]
MFLILLISLPMAFAVIGDLKCTTVSINDVDTGVPSISTDTVDVTNGLGTYYVLDRVYLNTTLLLNGYYPT
SGSTYRNMALKGTLLLSTLWFKPPFLSDFTNGIFAKVKNTKVIKDGVMYSEFPAITIGSTFVNTSYSVVV
QPHTTNFDSKLQGLLEISVCQYTMCEYPNTICNPNLGNQRVELWHWDTGVVSCLYKRNFTYDVNADYLYF
HFYQEGGTFYAYFTDTGVVTKFLFNVYLGTVLLHYYVMPLTCNSALTLEYWVTPLTSKQYLLAFNQDGVI
FNAVDCKSDFMSEIKCKTLSIAPSTGVYELNGYTVQPIADVYRRIPNLPDCNIEAWLNDKSVPSPLNWER
KTFSNCNFNMSSLMSFIQADSFTCNNIDAAKIYGMCFSSITIDKFAIPNGREVDLQLGNLGHLPTFNYRI
ETTARSCQLYYNLPAANVSVSRFNPSTWNRRFGFIEQSVFKPQPAGVFTDHDVVYAQHCFKAPTNFCPCK
LDGSLCVGSGSGIDAGYKNTGIGTCPAGTNYLTCHNAAQCDCLCTPDPITSKATGPYKCPQTKYLVGIGE
HCSGLAIKSDYCGGNPCSCQPQAFLGWSVDSCLQGDRCNIFANFILHDVNSGTTCSTDLQKSNTDIILGV
CVNYDLYGITGQGIFVEVNATYYNSWQNLLYDSNGNLYGFRDYLTNRTFMIRSCYSGRVSAAFHANSSEP
ALLFRNIKCNYVFNNTLSRQLQPINYFDSYLGCVVNADNSTSRCVKPCDLTVGSGYCVDYSTKRRSRRSI
TTGYRFTNFEPFTVNSVNDSLEPVGGLYEIQIPSEFTIGNMEEFIQTSSPKVTIDCSAFVCGDYAACKSQ
LVEYGSFCDNINAILTEVNELLDTTQLQVANSLMNGVTLSTKLKDGVNFNVDDINFSPVLGCLGSDCNKV
SSRSAIEDLLFSKVKLSDVGFFEAYNNCTGGAEIRDLICVQSYNGIKVLPPLLSENQISGYTSAATSASL
FPPWSAAAGVPFYLNVQYRINGIGVTMDVLSQNQKIIANAFNNALGAIQDGFDATNSALVKIQAVVNANA
EALNNLLQQLSNRFGAISSSLQEILSRLDALEAQAQIDRLINGRLTALNAYVSQQLSDSTLVKFSAAQAM
EKVNECVKSQSSRINFCGNGNHIISLVPHAPYGLYFIHFSYVPTKYVTAKVSPGLCIAGDRGIAPKSGYF
VNVNNTWMFTGSGYYYPEPITGNNVVVMSTCAVNYTKAPDVMLNISTPNLPDFKEELDQWFKNRTSVAPD
LSLDYKNVTFLDLQDEMNRLQEAIKVLNQSYINLKDIGTYEYYVKWPWYVWLLIGFAGVAMLVLLFFICC
CTGCGTSRFKICGGCCDDYAGHQELVIKTSHDD
>Murine S glycoprotein [murine hepatitis virus] 
GLGVLEDKCGGSNTCNCSADAFVGWAKDSCLSNGRCHIFGNLLLNGINSGTTCSTDLQLPNTEVVTGVCV
KYDLYGITGQGVFKEVKADYYNSWQNLLYDVNGNLMGFRDIVTNKTYLIRSCYSGRVSAAYHQDAPEPAL
LYRNLKCDYVFNNNISREETPLNYFDSYLGCVVNADNSTEQSVGACDLRMGSGLCVNYSTAHRARRSVST
GYKLTTFEPFTVSIVNDSVESVGGLYEMQIPINFTIASHQEFIQTRSPKVTIDCAAFVCGDYAACRQQLI
EYGSFCDNINAILGEVNNLIDTMQLQVASALIQGVTLSSRLADGISGQIDDINFSPLLGCLGSQCSEGTM
AAQGRSTIEDLLFDKVKLSDVGFVEAYNNCTGGQEVRDLLCVQSFNGIKVLPPVLSENQISGYTAGATAS
SMFPPWSAAAGVPFSLSVQYRINGLGVTMNVLSENQKMIASAFNNAIGAIQEGFDATNSALAKIQSVVNA
NAEALNNLLNQLSNRFGAISASLQEILSRLDALEAQAQIDRLINGRLTALNAYVSKQLSDMTLIKVSAAQ
AIEKVNECVKSQSPRINFCGNGNHILSLVQNAPYGLYFIHFSYVPTSFTTVNVSPGLCISGDRGLAPKAG
YFIQDNGEWMFTGSNYYYPEPINDKNSVVMSSCAVNYTKAPEVFLNTSIPNLPDFKEELDKWFKNQTSVA
PDLSLDFEKLNVTFLDLSDEMNRIQEAIKKLNESYINLKEVGTYEMYVKWPWYVWLLIGLAGVAVCVLLF
FICCCTGCGSCCFKKCGNCCDEYGGHQDSIVIHNISSHED
>Rat spike protein [rat sialodacryoadenitis coronavirus] 
MLFVFLTLLPSCLGYIGDFRCINLVNTRISNARAPSVSTEVVDVSKGLGTYYVLDRVYLNATLLLTGYYP
VDGSMYRNMALMGTNTLSLNWFEPPFLSEFNDGIYAKVKNLKASLPIGSASYFPTIIIGSNFVNTSYTVV
LEPYNGIIMASICQYTICQLPHTDCKPNTGGNTLIGFWHTDLRPPVCILKRNFTFNVNAEWLYFHFYQQG
GTFYAYYADVSSATTFLFSSYIGAVLTQYFVLPYMCSPTTSGVSSPQYWVTPLVKRQYLFNFNQKGIITS
AVDCASSYTSEIKCKTQSMNPNTGVYDLSGYTVQPVGLVYRRVRNLPDCKIEEWLAANTVPSPLNWERKT
FQNCNFNLSSLLRFVQAESLSCSNIDASKVYGMCFGSISIDKFAIPNSRRVDLQLGKSGLLQSFNYKIDT
RATSCQLYYSLAQDNVTVINHNPSSWNRRYGFNDVATFHSGEHDVAYAEACFTVGASYCPCAKPSTVYSC
VTGKPKSANCPTGTSNRECNVQASGFKSKCDCTCNPSPLTTYDPRCLQARSMLGVGDHCEGLGILEDKCG
GSNICNCSADAFVGWAMDSCLSNARCHIFSNLMLNGINSGTTCSTDFQLPNTEVVTGVCVKYDLYGSTGQ
GVFKEVKADYYNSWQNLLYDVNGNLNGFRDIVTNKTYLLRSCYSGRVSAAYHQDAPEPALLYRNLKCDYV
FNNNISREETPLNYFDSYLGCVINADNSTEQSVDACDLRMGSGLCVNYSIAHRARRSVSTGYKLTTFEPF
TVSIVNDSVESVGGLYEMQIPTNFTIASHQEFIQTRSPKVTIDCAAFVCGDYTACRQQLVDYGSFCDNIN
AILGEVNNLIDTMQLQVASALIQGVTLSSRLADGISGQIDDINFSPLLGCLGSDCSEGTKAAQGRSAIED
VLFDKVKLSDVGFVESYNNCTGGQEVRDLLCVQSFNGIKVLPPVLSESQISGYTAGATASAMFPPWSAAA
GVPFALSVQYRINGLGVTMNVLSENQKMIASSFNNAIGAIQEGFDATNSALAKIQSVVNANAEALNNLLN
QLSNRFGAISASLQEILSRLDALEAQAQIDRLINGRLTALNAYVSKQLSDMTLIKVSAAQAIEKVNECVK
SQSPRINFCGNGNHILSLVQNAPYGLYFIHFSYVPTSFTTVNVSPGLCISGDRGLAPKAGYFVQDHGEWK
FTGSNYYYPESITDKNSVVMSSCAVNYTKAPEVFLNTSITNLPDFKEELDKWFKNQTSIVPDLSFDIGKL
NVTFLDLSYEMNRIQDAIKNLNESYINLKEIGTYEMYVKWPWYVWLLIGLAGVAVCVLLFFICCCTGCGS
CCFKKCGNCCDEYGGRQAGIVIHNISSHED
>SARS spike [SARS coronavirus ShanghaiQXC2]
MFIFLLFLTLTSGSDLDRCTTFDDVQAPNYTQHTSSMRGVYYPDEIFRSDTLYLTQDLFLPFYSNVTGFH
TINHTFGNPVIPFKDGIYFAATEKSNVVRGWVFGSTMNNKSQSVIIINNSTNVVIRACNFELCDNPFFAV
SKPMGTQTHTMIFDNAFNCTFEYISDAFSLDVSEKSGNFKHLREFVFKNKDGFLYVYKGYQPIDVVRDLP
SGFNTLKPIFKLPLGINITNFRAILTAFSPAQDIWGTSAAAYFVGYLKPTTFMLKYDENGTITDAVDCSQ
NPLAELKCSVKSFEIDKGIYQTSNFRVVPSGDVVRFPNITNLCPFGEVFNATKFPSVYAWERKKISNCVA
DYSVLYNSTFFSTFKCYGVSATKLNDLCFSNVYADSFVVKGDDVRQIAPGQTGVIADYNYKLPDDFMGCV
LAWNTRNIDATSTGNYNYKYRYLRHGKLRPFERDISNVPFSPDGKPCTPPALNCYWPLNDYGFYTTTGIG
YQPYRVVVLSFELLNAPATVCGPKLSTDLIKNQCVNFNFNGLTGTGVLTPSSKRFQPFQQFGRDVSDFTD
SVRDPKTSEILDISPCAFGGVSVITPGTNASSEVAVLYQDVNCTNVSAAIHADQLTPAWRIYSTGNNVFQ
TQAGCLIGAEHVDTSYECDIPIGAGICASYHTVSLLRSTSQKSIVAYTMSLGADSSIAYSNNTIAIPTNF
SISITTEVMPVSMAKTSVDCNMYICGDSTECANLLLQYGSFCTQLNRALSGIAAEQDRNTREVFAQVKQM
YKTPTLKYFGGFNFSQILPDPLKPTKRSFIEDLLFNKVTLADAGFMKQYGECLGDINARDLICAQKFNGL
TVLPPLLTDDMIAAYTAALVSGTATAGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKQIANQFN
KAISQIQESLTTTSTALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLIT
GRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQAAPHGVVFLHVTYV
PSQERNFTTAPAICHEGKAYFPREGVFVFNGTSWFITQRNFFSPQIITTDNTFVSGNCDVVIGIINNTVY
DPLQPELDSFKGELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQ
YIKWPWYVWLGFIAGLIAIVMVTILLCCMTSCCSCLKGACSCGSCCKFDEDDSEPVLKGVKLHYT